Pulmonary hypertension Birth Disease

  • introduction;
  • a pathological condition characterized by elevation of pressure in the pulmonary arterial system more than upper limit of normal.30 mm hg systolic, 15 mm hg distolic cause of pulmonary hypertension
  • Mitral stenosis,
  • LV failure,
  • alveolar hypoxia,
  • high altitude exposure.
  • Obstructive , due to increase in pulmonary vascular resistance.
  • obstructive military emboli
  • obliterative
  • Chronic bronchitis and emphysema,
  • severe lungs fibrosis,
  • Hyperkinetic,
  • PDA ,ASD, VSD
  • miscellaneous;
  • liver cirrhosis, sickle cell Disease,toxin mediated
  • Murmur, systolic ejection, murmur, due to blood ,flow through, dilated, pulmonary,artery
  • Early distolic murmur,
  • Investigation;
  • ECG RV and often, RA hypertrophy
  • Chest radiography, prominent, main pulmonary arteries, but peripheral lungs
    • Special diagnosis;
    • echocardiography,
    • cardiac catheterization,
    • arterial blood ges,
    • pulmonary function test,
    • ventilator perfusion lungs scans,
    • high resolution CT scan,
    • Lungs biopsy,
    • Differential diagnosis
    • Damped mitral stenosis
    • Chronic thromboembolic, pulmonary hypertension
    • Management!
    • cardiac pulmonary Disease
    • calcium channel blocker, Chronic ogygen therapy,
    • Postacyclin analogue,
    • Epoprostenol,
    • Endothelial -recepter antagonist, heart lungs transplanted

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